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_______ what his parents think, he is leaving home for a new job in a big city.

A. Regardless of                        B. Instead of

C. In terms of                         D. Lack of

解析:选A。句意:不管他父母怎么想的,他还是要离开家,去一所大城市找份新工作。regardless of不管,不顾;instead of代替;in terms of鉴于;lack of缺乏。

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