__________ the fact that there was thick fog, he drove his car out.
A. Although     B. No matter    C. Despite    D. In spite

__________ the fact that there was thick fog, he drove his car out.
A. Although     B. No matter    C. Despite    D. In spite

      the fact that there was thick fog,he drove his car out.

A.Despite                    B.In spite

C.Although                   D.No matter how